Golshani Lab

Research Mission

Our mission is to understand how large-scale neuronal population activity patterns in specific cell-types drive cognition. And to determine how these activity patterns become corrupted in models of neurological and neurodevelopmental disorders.

We have developed or adapted behavioral assays involving attention, working memory, spatial navigation and social motivation. We couple these behaviors with a variety of techniques including miniaturized microscopy, in-vivo two-photon imaging, voltage imaging, whole-cell and extracellular electrophysiology, optogenetics and single-cell RNA sequencing to identify hubs and critical neuronal cell types that can be targeted to improve cognition in models of disease.